Companies around the world invest billions in R&D to provide cutting-edgeinnovation to their products and services. In order to protect these investments, companies apply for patents. Therefore, the number of utility patents a company is granted can be considered a rough measure of its level of innovation.Every year, the Patent 300 List identifies America’s most innovative companies within the intellectual property space by analyzing the patents granted by the United States Patent and Trademark Office (USPTO).In 2021, the USPTO granted a total of 327,798 utility patents, down 7% from the previous year. Let’s take a look at which companies generated the most patents in 2021.